Bidirectional translation of biomedical knowledge from the early research laboratory, through development and manufacturing to clinical & patient-oriented and population-based research
RNA-seq, scRNA-seq, or epigenome (e.g. ChIP-seq, Methylation sequencing) NGS or array-based, NGS-based analysis confirmation of genome edits at a targeted or genome-wide level, sgRNA design optimisation
16s/ITS Metagenomics & Meta-transcriptomics, pre-processing of raw data, dereplication of sequences and chimeric reads removal, OTU picking, Quality filtering, taxonomical classification
Exome and Whole Genome Sequence (WGS) variant calling and genome-wide association studies bioinformatics and data visualisation support
Spatial multiomics integration, Next Generation Sequencing (NGS), array based gene expression analysis, bulk and single-cell RNA-seq, epigenetic data integration, spatial transcriptomics.
Bioinformatics supporting genome-wide landscape of modifications such as DNA methylation, DNA-protein interactions, chromatin accessibility, histone modifications etc.
Manipulation of biology at the 'Omic level and its downstream effects uses many different techniques such cloning, plasmid design, cell transfection and protein/product production.
Ontology definition and governance in commercial and open-source platforms alongside deep domain and technical knowledge to support your FAIR and semantic data journey.